The distribution of free amino acids between erythrocytes and plasma in man.
نویسندگان
چکیده
In man, the relative concentrations of a-amino nitrogen in tungstic acid filtrates of erythrocytes and plasma have been determined by Hamilton and Van Slyke, using the ninhydrin method (2). Dunn et al. (3) reported assays of free tryptophan in blood serum, plasma, and red blood cells by microbiological means with Lactobacillus arabinosus. More recently, Gutman and Alexander (4) determined the level of free glycine and alanine in plasma and red cells by chemical methods under fasting and non-fasting conditions. The plasma levels of ten individual amino acids in thirtythree normal men and women have been previously reported from this laboratory (5). There is being reported here the concentrations of twelve amino acids determined simultaneously in the red blood cells and in the plasma of twenty-four normal men.
منابع مشابه
Study of Human Albumin Protein Interaction with Fluorouracil Anticancer Drug Using Molecular Docking Method
Introduction: Drugs are mainly delivered to the target tissues by plasma proteins, such as human serum albumin, in the human body. Practical information about the thermodynamic parameters of drugs and their stability can be obtained using simulation methods, such as molecular docking. Material & Methods: This study, investigated the molecular docking of human serum albumin with fluorouracil an...
متن کاملAnalysis of Plasma Amino Acids Using RP-HPLC and Pre-Column Derivatization with OPA/3-MPA
ABSTRACT Background and Objective: Measurement of amino acids is an important tool for metabolic studies and evaluation of patients’ clinical condition. The aim of this study was to analyze the plasma amino acids using reverse phase high performance liquid chromatography techniques (RP-HPLC) with pre-column derivatization by o-phthalaldehyde (OPA)...
متن کاملEVALUATION OF METABOLIC PROFILE OF PLASMA AMINO ACIDS IN DIABETIC PATIENTS WITH CARDIOVASCULAR DISEASES
Background: Diabetes mellitus is one of the most common endocrine diseases. Cardiovascular disease (CVD) is one of the leading causes of death in patients with type 2 diabetes. The aim of this study was to investigate the metabolic profile of plasma amino acids in diabetic patients with cardiovascular disease. Methods: The present study is a descriptive-analytical cross-sectional study on 140 ...
متن کاملTheoretical study of the solvent effects on the thermodynamic functions of Alanine and Valine Amino Acids
Using Gaussian 03, software the thermodynamic functions such as Gibbs free energy, G, Enthalpy, H, and Entropy, S, of Alanine and Valine amino acids were theoretically studied at different solvents. First, the Density Functional Theory (B3LYP) level with 3-21G, 6-31G and 6-31+G basis sets were employed to optimization of isolated Alanine and Valine amino acids in the gas phase. Moreover, Vib...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Journal of biological chemistry
دوره 188 2 شماره
صفحات -
تاریخ انتشار 1951